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UPDATE: Regulatory Changes May Affect Your Compounded Preparations

Domperidone

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This product requires refrigeration, and must be shipped overnight.
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Product Description

Domperidone is commonly prescribed for fescue toxicosis. Endophyte-infected fescue grass is commonly found in and around pastures throughout most of the United States, with a particularly high prevalence in the Southern Regions. Toxins produced by the fungal endophyte, Neotyphodium coenophialum, that grows in fescue, depress the hormones necessary for normal labor, delivery, and lactation in mares. Domperidone counteracts the effects of the fungal toxins by competitively blocking dopamine receptors.
 
Mares that develop fescue toxicosis have increased gestation lengths, poor udder development, low or no milk production, and are prone to a high incidence of premature placental separation or retained placentas, difficult deliveries, and large, weak foals with increased foal and mare mortality. Use of domperidone as prescribed during pregnancy and after foaling greatly reduces complications and aids in milk production.
 
 

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